The research behind NeuroCatch®
Since the earliest evoked responses were reported in 1939, there are now over 170,000 published studies on the PubMed.gov database.
The NeuroCatch® platform measures three event-related potentials (ERPs) that are direct measures of cognitive function: N100, P300, and N400 responses, for which over 103,600 studies have been published.
Brain Vital Signs
Objective Neurophysiological Measures of Cognitive Performance in Elite Ice Hockey Players
- Kirby ED, Jones K, Campbell N, Fickling SD, and D’Arcy RCN
- 2025
- Open Access Journal of Sports Medicine. 16 (January):15–24
- https://doi.org/10.2147/OAJSM.S494589
A retrospective, observational study of real-world clinical data from the Cognitive Function Development Therapy program
- Kirby ED, Beyst B, Beyst J, Brodie SM and D’Arcy RCN
- 2024
- Front. Hum. Neurosci. 18:1508815
- doi: 10.3389/fnhum.2024.1508815
An objective neurophysiological study of subconcussion in female and male high school student athletes
- D’Arcy R. C. N., McCarthy D., Harrison D., Levenberg Z., Wan J., Hepburn A., Kirby E. D., Yardley T., Yamada-Bagg N., Fickling S. D., Munce T. A., Dodick D. W., Ahmad C., & Stein K. S.
- 2024
- Scientific reports, 14(1), 28929
- https://doi.org/10.1038/s41598-024-80262-z
Brain vital sign monitoring of sleep deprivation detects situational cognitive impairment
- Jones KB, Frizzell T, Fickling SD, Pawlowski G, Brodie SM, Lakhani B, Venter J, D’Arcy RCN
- 2024
- Frontiers in Human Neuroscience
- https://doi.org/10.3389/fnhum.2024.1358551
Brain vital signs as a quantitative measure of cognition: Methodological implementation in a care home environment
- Ighalo J, Kirby ED, Song X, Fickling SD, Pawlowski G, Ghosh Hajra S, Liu CC, Menon C, Shah SA, Knoefel F, D’Arcy RCN
- 2024
- Heliyon
- https://doi.org/10.1016/j.heliyon.2024.e28982
Mixed martial art athletes demonstrate different brain vital sign profiles compared to matched controls at baseline
- Munce T.A., Fickling S.D., Nijjer S., Poel D.N., & D’Arcy R.C.N.
- 2024
- Frontiers in Neurology, 15.
- https://doi.org/10.3389/fneur.2024.1438368
Real world evidence of improved attention and cognition during physical therapy paired with neuromodulation: a brain vital signs study
- Kirby ED, Jones CB, Fickling SD, Pawlowski G, Brodie SM, Boyd LA, Venter J, Moser N, Kalsi-Ryan S, Medvedev G and D’Arcy RCN
- 2023
- Frontiers in Human Neuroscience. 17:1209480
- doi: 10.3389/fnhum.2023.1209480
A Practical and Accessible Measure of Brain Vital Signs: the NeuroCatch® Platform
- D’Arcy, R.C.N., Campbell, N., Fickling S.
- 2022
- NeuroCatch Inc.
- TBD
Distant Sensor Prediction of Event-Related Potentials
- Fickling, S.D., Bolinger, F., Pawlowski, G., Ghosh Hajra, S., Liu, C.C., Song, X., & D’Arcy, R.C.N.
- 2022
- IEEE Transactions on Biomedical Engineering. 67(10), 2916 – 2924
- doi: 10.1109/TBME.2020.2973617
Objective neurophysiological markers of cognition after pediatric brain injury
- Nayoung Kim, William D. Watson, Eric Caliendo, Sophie Nowak, Nicholas D. Schiff, Sudhin A. Shah, N. Jeremy Hill
- 2022
- Neurology Clinical Practice
- 10.1212/CPJ.0000000000200066. (Independent Study)
Brain Vital Signs in Elite Ice Hockey: Towards Characterizing Objective and Specific Neurophysiological Reference Values for Concussion Management
- Carrick, F. R., Pagnacco, G., Azzolino, S. F., Hunfalvay, M., Oggero, E., Frizzell, T., Smith, C. J., Pawlowski, G., Campbell, N., Fickling, S. D., Lakhani, B., & D’Arcy, R.
- 2021
- Frontiers in neuroscience, 15, 670563
- https://doi.org/10.3389/fnins.2021.670563
Event Related Potential Signal Capture Can Be Enhanced through Dynamic SNR-Weighted Channel Pooling
- Hajra, S. G., Liu, C. C., Fickling, S. D., Pawlowski, G. M., Song, X., & D’Arcy, R.
- 2021
- Sensors (Basel, Switzerland), 21(21), 7258
- https://doi.org/10.3390/s21217258
Mitigating Long-Term COVID-19 Consequences on Brain Health
- D’Arcy, R., Sandhu, J. K., Marshall, S., & Besemann, M.
- 2021
- Frontiers in neurology, 12, 630986
- https://doi.org/10.3389/fneur.2021.630986
Subconcussive brain vital signs changes predict head-impact exposure in ice hockey players
- Fickling, S. D., Smith, A. M., Stuart, M. J., Dodick, D. W., Farrell, K., Pender, S. C., & D’Arcy, R. C.
- 2021
- Brain Communications, 3(2), fcab019
- doi:10.1093/braincomms/fcab019
Subconcussive changes in youth football players: Objective evidence using brain vital signs and instrumented accelerometers
- Fickling, S.D., Poel, D.N., Dorman, J.C., D’Arcy, R.C.N., & Munce, T.A.
- 2021
- Brain Communications, fcab286
- https://doi.org/10.1093/braincomms/fcab286
Brain vital signs detect information processing differences when neuromodulation is used during cognitive skills training
- Smith, C., Lakhani, B., Livingstone, A., Fickling, S., Campbell, N., Tannouri, P., Danilov, Y., Sackier, J., & D’Arcy, R.C.N.
- 2020
- Frontiers in Human Neuroscience. 14, 358.
- doi: 10.3389/fnhum.2020.00358
Brain vital signs detect concussion-related neurophysiological impairment in ice-hockey
- Fickling, S.D., Smith, A.M., Pawlowski, G., Ghosh Hajra, S., Liu, C.C., Farrell, K., Jorgensen, J., Song, X., Stuart, M.J., D’Arcy, R.C.N.
- 2019
- Brain, 142(2), 255-262. Editor’s Choice.
- doi: 10.1093/brain/awy317
Brain vital signs: Expanding from the auditory to visual modality
- Pawlowski, G., Ghosh Hajra, S., Fickling, S., Liu, C.C., Song, X., Robinovitch, S., Doesburg, S.M., & D’Arcy, R.C.N.
- 2019
- Frontiers in Neuroscience. 18;12:968.
- doi: 10.3389/fnins.2018.00968
Good data? The EEG quality index for automated assessment of signal quality
- Fickling, S.D., Liu, C.C., Ghosh Hajra, S., Song, X., & D’Arcy, R.C.N.
- 2019
- IEEE XPlore. 2019, 0219-0229.
- doi: 10.1109/IEMCON.2019.8936246
Proceedings from the Ice Hockey Summit III: Action on Concussion
- Smith, A.N., Alford, P.A., Aubry, M., Benson, B., Black, A., Brooks, A., Burke, C., D’Arcy, R.C.N., Dodick, D., Eaves, M., Eickhoff, C., Erredge, K., Farrell, K., Finnoff, J., Fraser, D., Giza, C., Greenwald, R., Hanzel, M., Hoshizaki, B., Huston, J., Jorgenson, J., Joyner, M., Krause, D., LaVoi, N., Leaf, M., Leddy, J., Leopold, J., Margarucci, K., Margulies, S., Mihalik, J., Munce, T., Ouer, A., Podein, S., Prideaux, C., Roberts, W.O., Shen, F., Soma, D., Tabrum, M., Stuart, M.B., Wethe, J., Whitehead, J., Wiese-Bjornstal, D., & Stuart, M.J.
- 2019
- Current Sport Medicine Reports, 18(1), 23-34.
- doi: 10.1249/JSR.0000000000000557
Reply: P300 amplitudes after concussion are usually decreased not increased
- Fickling, S.D., Smith, A.M., Pawlowski, G., Ghosh Hajra, S., Liu, C.C., Farrell, K., Jorgensen, J., Song, X., Stuart, M.J., & D’Arcy, R.C.N.
- 2019
- Brain.142(7), e33
- doi: 10.1093/brain/awz147
Accessing knowledge of the ‘here and now’: A new technique for capturing electromagnetic markers of orientation processing
- Ghosh Hajra, S., Liu, C.C., Song, X., Fickling, S.D., Cheung, T.P.L. & D’Arcy, R.C.N.
- 2018
- Journal of Neural Engineering, 16(1), 016008.
- doi: 10.1088/1741-2552/aae91e
Multimodal characterization of the semantic N400 response within a rapid evaluation brain vital sign framework
- Ghosh Hajra, S., Liu, C.C., Song, X., Fickling, S.D., Cheung, T.P., & D’Arcy, R.C.N.
- 2018
- Journal of Translational Medicine, 16(1),151.
- doi: 10.1186/s12967-018-1527-2
Developing Brain Vital Signs: Initial Framework for Monitoring Brain Function Changes Over Time
- Ghosh-Hajra, S., Liu, C., Song, X., Fickling, S., Pawlowski, G., Jorgensen, J.K., Smith, A.M., Schnaider-Beeri, M., Van Den Broek, R., Rizzotti, R., Fisher, K., & D’Arcy, R.C.N.
- 2016
- Frontiers of Neuroscience, Brain Imaging Methods. 10, 211.
- doi: 10.3389/fnins.2016.00211
Supporting Clinical ERP/EEG Literature
Investigating female versus male differences in white matter neuroplasticity associated with complex visuo-motor learning
- Kirby, E. D., Andrushko, J. W., Rinat, S., D’Arcy, R. C. N., & Boyd, L. A.
- 2024
- Scientific reports, 14(1), 5951
- https://doi.org/10.1038/s41598-024-56453-z
Imaging functional neuroplasticity in human white matter tracts
- Frizzell, T. O., Phull, E., Khan, M., Song, X., Grajauskas, L. A., Gawryluk, J., & D’Arcy, R.
- 2022
- Brain structure & function, 227(1), 381–392.
- https://doi.org/10.1007/s00429-021-02407-4
audiomath
- Hill, N. J., Mooney, S., & Prusky, G. T.
- 2021
- A neuroscientist’s sound toolkit. Heliyon, 7(2), e06236.
- doi.org/10.1016/j.heliyon.2021.e06236
The Pupillary Light Reflex as a Biomarker of Concussion
- Carrick, F. R., Azzolino, S. F., Hunfalvay, M., Pagnacco, G., Oggero, E., D’Arcy, R., Abdulrahman, M., & Sugaya, K.
- 2021
- Life (Basel, Switzerland), 11(10), 1104.
- https://doi.org/10.3390/life11101104
Differential neural processing of spontaneous blinking under visual and auditory sensory environments: An EEG investigation of blink-related oscillations
- Liu, C.C., Ghosh Hajra, S., Pawlowski, G., Fickling, S.D., Song, X., & D’Arcy, R.C.N.
- 2020
- NeuroImage. 218, 116879
- https://doi.org/10.1016/j.neuroimage.2020.116879
Portable neuromodulation induces neuroplasticity to re-activate motor function recovery from brain injury: a high-density MEG case study
- D’Arcy, R. C. N., Greene, T., Greene, D., Frehlick, Z., Fickling, S. D., Campbell, N., Etheridge, T., Smith, C., Bollinger, F., Danilov, Y., Livingstone, A., Tannouri, P., Martin, P., & Lakhani, B.
- 2020
- Journal of neuroengineering and rehabilitation, 17(1), 158.
- https://doi.org/10.1186/s12984-020-00772-5
The Feasibility of Longitudinal Upper Extremity Motor Function Assessment Using EEG
- Zhang, X., D’Arcy, R.C.N., Ming, D., & Menon, C.
- 2020
- TBD
- https://doi.org/10.3390/s20195487
Cognitive loading via mental arithmetic modulates effects of blink-related oscillations on precuneus and ventral attention network regions
- Liu, C.C., Ghosh Hajra, S., Song, X., Doesburg, S., Cheung, T.P.L., & D’Arcy, R.C.N.
- 2019
- Human Brain Mapping, 40(2), 377-393
- https://doi.org/10.1002/hbm.24378
Electrophysiology of inhibitory control in the context of emotion processing in children with autism spectrum disorder
- Magnuson, J.R., Peatfield, N.A., Fickling, S., Nunes, A.S., Christie, G., Vakorin, V., D’Arcy, R.C.N., Ribary, U., Iarocci, G., Moreno, S., & Doesburg, S.M.
- 2019
- Frontiers in Human Neuroscience. 12,13:78
- https://doi.org/10.3389/fnhum.2019.00078
Human translingual neurostimulation alters resting brain activity in high-density EEG
- Frehlick, Z., Lakhani, B., Fickling, S., Livingstone, A., Danilov, Y., Sackier, J., & D’Arcy, R.C.N.
- 2019
- Journal of NeuroEngineering and Rehabilitation. 16(1), 60
- https://doi.org/10.1186/s12984-019-0538-4
Novel signal processing technique for capture and isolation of blink-related oscillations using a low-density electrode array for bedside evaluation of consciousness
- Liu, C.C., Ghosh Hajra, S., Fickling, S.D., Pawlowski, G., Song, X., & D’Arcy, R.C.N.
- 2019
- EEE Transactions on Biomedical Engineering. Epub ahead of print. 67(2), 453-463
- https://doi.org/10.1109/TBME.2019.2915185
Scoring upper-extremity motor function from EEG using artificial intelligence
- Zhang, X., D’Arcy, R.C.N., Menon, C.
- 2019
- Journal of Neural Engineering. 16 (3), 036013
- https://doi.org/10.1088/1741-2552/ab0b82
Point-of-care brain injury evaluation of conscious awareness: Wide scale deployment of portable HCS EEG evaluation
- Fleck-Prediger, C., Ghosh Hajra, S., Liu, C.C., Gray, S., Petley, L., Weaver, D.F., Gopinath, S., Yee, E., Dick, B.D., & D’Arcy, R.C.N.
- 2018
- Neuroscience of Consciousness. 2018(1)
- https://doi.org/10.1093/nc/niy011
Spontaneous blinks activate the precuneus: Characterizing blink-related oscillations using magnetoencephalography
- Liu, C.C.; Ghosh Hajra, S., Cheung, T.P., Song, X., & D’Arcy, R.C.N.
- 2017
- Frontiers in Human Neuroscience. 11, 489
- https://doi.org/10.3389/fnhum.2017.00489
Long-Term Motor Recovery After Severe Traumatic Brain Injury: Beyond Established Limits
- D’Arcy, R.C.N., Lindsay, D.S., Song, X., Gawryluk, J.R., Greene, D., Mayo, C., Ghosh Hajra, S., Mandziuk, L., Mathieson, J., & Greene T.
- 2016
- Journal of Head Trauma Rehabilitation. 31(5), E50-8
- https://doi.org/10.1097/HTR.0000000000000185
A rapid event-related potential (ERP) method for point-of-care evaluation of brain function: using ERPs: Development of the Halifax Consciousness Scanner
- Sculthorpe-Petley, L., Liu, C., Ghosh-Hajra, S., Boshra, R., Satel, J., Trappenberg, T.P., D’Arcy, R.C.N.
- 2015
- Journal of Neuroscience Methods. 245, 64-72
- https://doi.org/10.1016/j.jneumeth.2015.02.008
Detection of event-related potentials in individual subjects using support vector machines
- Parvar, H., R., Sculthorpe-Petley, L., Satel, J., Boshra, D’Arcy, R.C.N., Trappenberg, T.P.
- 2015
- Brain Informatics. 2 (1), 1-12
- https://doi.org/10.1007/s40708-014-0006-7
Towards brain first-aid: A diagnostic device for conscious awareness
- D’Arcy, R.C.N., Ghosh-Hajra, S., Liu, C., Sculthorpe, L., & Weaver, D.F.
- 2011
- IEEE Transactions on Biomedical Engineering. 58(3), 750-4.
- https://doi.org/10.1109/TBME.2010.2090880
Event-related brain potentials as a measure of performance on WISC-III and WAIS-R NI Similarities sub-tests
- Connolly, J.F., Marchand, Y., Major, A., & D’Arcy, R.C.N.
- 2006
- Journal of Clinical and Experimental Neuropsychology. 28(8), 1327-1345
- https://doi.org/10.1080/13803390500428484
The influences of increased working memory load on semantic neural systems: A high-resolution event-related brain potential study
- D’Arcy, R.C.N., Service, E., Connolly, J.F., & Hawco, C.S.
- 2005
- Cognitive Brain Research. 22 (2), 177-191
- https://doi.org/10.1016/j.cogbrainres.2004.08.007
Separating phonological and semantic processing in auditory sentence processing: A high-resolution event-related brain potential study
- D’Arcy, R.C.N., Connolly, J.F., Service, E., Hawco, C.S., & Houlihan, M.E.
- 2004
- Human Brain Mapping. 22 (1), 40-51
- https://doi.org/10.1002/hbm.20008
Electrophysiological assessment of language function following stroke
- D’Arcy, R.C.N., Marchand, Y., Eskes, G.A., Harrison, E.R, Major, A., Phillips, S.J., & Connolly, J.F.
- 2003
- Clinical Neurophysiology. 114 (4), 662-672
- https://doi.org/10.1016/S1388-2457(03)00007-5
Linking neurophysiological and neuropsychological measures for aphasia assessment
- Marchand, Y., D’Arcy, R.C.N., & Connolly, J.F.
- 2002
- Clinical Neurophysiology. 113(11), 1715-22
- https://doi.org/10.1016/S1388-2457(02)00224-9
Phonological aspects of word recognition as revealed by high-resolution spatio-temporal brain mapping
- Connolly, J.F., Service, E., D’Arcy, R.C.N., Kujala, A., & Alho, A.
- 2001
- NeuroReport, 12(2), 237-43
- https://doi.org/10.1097/00001756-200102120-00012
Evaluation of reading comprehension with neuropsychological and event-related brain potential (ERP) methods
- D’Arcy, R.C.N., Connolly, J.F., & Eskes, G.A.
- 2000
- Journal of the International Neuropsychological Society. 6(5), 556-67
- https://doi.org/10.1017/S1355617700655054
Innovations in neuropsychological assessment using event-related brain potentials
- Connolly, J.F., & D’Arcy, R.C.N.
- 2000
- International Journal of Psychophysiology. 37(1), 31-47
- https://doi.org/10.1016/S0167-8760(00)00093-3
Latency shifts in the N2b component track phonological deviations in spoken words
- D’Arcy, R.C.N., Connolly, J.F., & Crocker, S.F.
- 2000
- Clinical Neurophysiology. 111(1), 40-4
- https://doi.org/10.1016/S1388-2457(99)00210-2
The application of cognitive event-related brain potentials in language-impaired individuals: Review and case studies
- Connolly, J.F., D’Arcy, R.C.N., Newman R.L. & Kemps, R.
- 2000
- International Journal of Psychophysiology. 38(1), 55-70
- https://doi.org/10.1016/S0167-8760(00)00130-6
An event-related brain potential study of receptive speech comprehension using a modified Token Test
- D’Arcy, R.C.N., & Connolly, J.F.
- 1999
- Neuropsychologia. 37(13), 1477-1489.
- https://doi.org/10.1016/S0028-3932(99)00057-3
Performance on WISC-III and WAIS-R NI vocabulary subtests assessed with event-related brain potentials: An innovative method of assessment
- Connolly, J.F., Major, A.M., Allen, S.L., & D’Arcy, R.C.N.
- 1999
- Journal of Clinical and Experimental Neuropsychology. 21(4), 444-464
- https://doi.org/10.1076/jcen.21.4.444.879